Basic Information:

Storage: Rabbit IgG in 10mM phosphate buffered saline, pH7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.Store at +4℃ short term. Store at -20℃ long term. Avoid repeated freeze-thaw cycle.

Background: Beta-catenin is an adherens junction protein. Adherens junctions (AJs; also called the zonula adherens) are critical for the establishment and maintenance of epithelial layers, such as those lining organ surfaces. AJs mediate adhesion between cells, communicate a signal that neighboring cells are present, and anchor the actin cytoskeleton. In serving these roles, AJs regulate normal cell growth and behavior.

	Western blot analysis of beta catenin expression in (1) A431 cell lysates; (2) PC-12 cell lysates.
	Immunohistochemistry showing positive staining in Breast carcinoma tissue.

For Research Use Only. Not for Use in Diagnostic Procedures.