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Anti-p21 Recombinant Rabbit Monoclonal Antibody

应用范围: WB, IHC-P, IHC-F, ICC/IF, IP
产品类型: 兔单抗
保存温度: -20℃
产地: YOBIBIO
UniProt ID: P38936
宿主: Rabbit
克隆性: Monoclonal
修饰: Unmodified
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Basic Information:

UniProt ID: P38936

Calculated Mol Weight: 18 kDa

Host: Rabbit

Observed Mol Weight: 21 kDa

Clonality: Monoclonal

Reactivity: Human

Source: Recombinant Rabbit mAb

Applications: WB, IHC-P, IHC-F, ICC/IF, IP

Isotype: Rabbit IgG

Purification: Affinity-chromatography

Modification: Unmodified

Immunogen: A synthesized peptide

Aliases: CAP20; CDKN1; CIP1; MDA-6; P21; SDI1; WAF1; p21CIP1; p21 CDKN1A

Recommended Dilutions: 

Storage: Rabbit IgG in 10mM phosphate buffered saline, pH7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.Store at +4 short term. Store at -20 long term. Avoid repeated freeze-thaw cycle.

Background: The tumor suppressor protein p21 Waf1/Cip1 acts as an inhibitor of cell cycle progression. It functions in stoichiometric relationships forming heterotrimeric complexes with cyclins and cyclin-dependent kinases. In association with CDK2 complexes, it serves to inhibit kinase activity and block progression through G1/S. However, p21 may also enhance assembly and activity in complexes of CDK4 or CDK6 and cyclin D.

Western blot analysis of p21 in (1) MCF-7 cell lysate; (2) LnCaP cell lysate.

For Research Use Only. Not for Use in Diagnostic Procedures. 


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保存温度:-20℃
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