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Anti-MEK1/2 Recombinant Rabbit Monoclonal Antibody

应用范围: WB, IHC-P, IHC-F, ICC/IF, IP
产品类型: 兔单抗
保存温度: -20℃
产地: YOBIBIO
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Basic Information:

UniProt ID: Q02750, P36507

Calculated Mol Weight: 43, 44 kDa

Host: Rabbit

Observed Mol Weight: 44 kDa

Clonality: Monoclonal

Reactivity: Human, Mouse, Rat

Source: Recombinant Rabbit mAb

Applications: WB, IHC-P, IHC-F, ICC/IF, IP

Isotype: Rabbit IgG

Purification: Affinity-chromatography

Modification: Unmodified

Immunogen: A synthesized peptide

Aliases: Dual specificity mitogen-activated protein kinase kinase 1; ERK activator kinase 1; MAP kinase kinase 1; MAP2K1; MAPK/ERK kinase 1; MAPKK1; MEK1; MP2K1; PRKMK1; kinase MEK1

Recommended Dilutions: 

WB 1:1000-1:2000

 

IHC-P 1:100-1:200

 

IHC-F 1:50-1:200

 

ICC/IF 1:50-1:200

 

IP 1:20-1:50

Storage:
Rabbit IgG in 10mM phosphate buffered saline, pH7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.Store at +4 short term. Store at -20 long term. Avoid repeated freeze-thaw cycle.

Background: Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Binding of extracellular ligands such as growth factors, cytokines and hormones to their cell-surface receptors activates RAS and this initiates RAF1 activation. RAF1 then further activates the dual-specificity protein kinases MAP2K1/MEK1 and MAP2K2/MEK2.

 

Western blot analysis of extracts from (1) 293T cells; (2) A549 cells, using MEK1/2 antibody.

For Research Use Only. Not for Use in Diagnostic Procedures. 

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