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Anti-LRP1 Recombinant Rabbit Monoclonal Antibody

应用范围: WB, IHC-P, IHC-F, ICC/IF, IP, FC
产品类型: 兔单抗
保存温度: -20℃
产地: YOBIBIO
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Basic Information:

UniProt ID: Q07954

Calculated Mol Weight: 505 kDa

Host: Rabbit

Observed Mol Weight: 85-100 kDa

Clonality: Monoclonal

Reactivity: Human, Mouse, Rat

Source: Recombinant Rabbit mAb

Applications: WB, IHC-P, IHC-F, ICC/IF, IP, FC

Isotype: Rabbit IgG

Purification: Affinity-chromatography

Modification: Unmodified

Immunogen: A synthesized peptide

Aliases: A2MR; alpha 2MR; Alpha 2 macroglobulin receptor; CD91; APR; LRP1; LRP85; TGFBR5

Recommended Dilutions: 

WB 1:1000-1:5000

 

IHC-P 1:100-1:200

 

IHC-F 1:50-1:200

 

ICC/IF 1:50-1:200

 

IP 1:20-1:50

 

FC 1:20-1:100

Storage: Rabbit IgG in 10mM phosphate buffered saline, pH7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.Store at +4 short term. Store at -20 long term. Avoid repeated freeze-thaw cycle.

Background: Endocytic receptor involved in endocytosis and in phagocytosis of apoptotic cells. Required for early embryonic development. Involved in cellular lipid homeostasis. Involved in the plasma clearance of chylomicron remnants and activated LRPAP1 (alpha 2-macroglobulin), as well as the local metabolism of complexes between plasminogen activators and their endogenous inhibitors. May modulate cellular events, such as APP metabolism, kinase-dependent intracellular signaling, neuronal calcium signaling as well as neurotransmission. Functions as a receptor for Pseudomonas aeruginosa exotoxin A.


Western blot analysis of LRP1 expression in A549 cell lysate.

For Research Use Only. Not for Use in Diagnostic Procedures. 

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保存温度:-20℃
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