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Anti-SOX2 Recombinant Rabbit Monoclonal Antibody

应用范围: WB, ICC/IF, IHC-P, IHC-F
产品类型: 兔单抗
保存温度: -20℃
产地: YOBIBIO
UniProt ID: P48431
宿主: Rabbit
克隆性: Monoclonal
修饰: Unmodified
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Basic Information:

UniProt ID: P48431

Calculated Mol Weight: 34 kDa

Host: Rabbit

Observed Mol Weight: 34 kDa

Clonality: Monoclonal

Reactivity: Human, Mouse, Rat

Source: Recombinant Rabbit mAb

Applications: WB, ICC/IF, IHC-P, IHC-F

Isotype: Rabbit IgG

Purification: Affinity-chromatography

Modification: Unmodified

Immunogen: A synthesized peptide

Aliases: SOX2; ANOP3; MCOPS3; MGC2413; lcc; SRY related HMG box 2

Recommended Dilutions:  

WB 1:1000-1:2000

 

ICC/IF 1:50-1:200

 

IHC-P 1:100-1:200

 

IHC-F 1:50-1:200

Storage: Rabbit IgG in 10mM phosphate buffered saline, pH7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. Store at +4 short term. Store at -20 long term. Avoid repeated freeze-thaw cycle.

Background: Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity). 

 

Western blot analysis of SOX2 expression in (1) NCCIT cell lysate; (2) F9 cell lysate.

For Research Use Only. Not for Use in Diagnostic Procedures. 

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保存温度:-20℃
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