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Anti-Cdk4 Recombinan Rabbit Monoclonal Antibody

应用范围: WB, ICC/IF, IP
产品类型: 兔单抗
保存温度: -20℃
产地: YOBIBIO
UniProt ID: P11802
宿主: Rabbit
克隆性: Monoclonal
修饰: Unmodified
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Basic Information:

UniProt ID: P11802

Calculated Mol Weight: 34 kDa

Host: Rabbit

Observed Mol Weight: 34 kDa

Clonality: Monoclonal

Reactivity: Human, Mouse, Rat

Source: Recombinant Rabbit mAb

Applications: WB, ICC/IF, IP

Isotype: Rabbit IgG

Purification: Affinity-chromatography

Modification: Unmodified

Immunogen: A synthesized peptide

Aliases: Cyclin-dependent kinase 4; Cell division protein kinase 4; PSK-J3; PSKJ3; CDK4; Crk3; CMM3

Recommended Dilutions:  

WB 1:1000-1:2000

 

ICC/IF 1:50-1:200

 

IP 1:20-1:50

Storage: Rabbit IgG in 10mM phosphate buffered saline, pH7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. Store at +4 short term. Store at -20 long term. Avoid repeated freeze-thaw cycle.

Background: Ser/Thr-kinase component of cyclin D-CDK4 (DC) complexes that phosphorylate and inhibit members of the retinoblastoma (RB) protein family including RB1 and regulate the cell-cycle during G1/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complexes and the subsequent transcription of E2F target genes which are responsible for the progression through the G1 phase.

Western blot analysis of CDK4 expression in HeLa cell lysate.

For Research Use Only. Not for Use in Diagnostic Procedures. 

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保存温度:-20℃
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