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Anti-Transferrin Receptor (CD71) Monoclonal Antibody

应用范围: WB, IHC-P, IP, FC
产品类型: 兔单抗
保存温度: -20℃
产地: YOBIBIO
UniProt ID: P02786
宿主: Rabbit
克隆性: Monoclonal
修饰: Unmodified
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Basic Information:

UniProt ID: P02786

Calculated Mol Weight: 85 kDa

Host: Rabbit

Observed Mol Weight: 90 kDa

Clonality: Monoclonal

Reactivity: Human, Mouse, Rat

Source: Recombinant Rabbit mAb

Applications: WB, IHC-P, IP, FC

Isotype: Rabbit IgG

Purification: Affinity-chromatography

Modification: Unmodified

Immunogen: A synthesized peptide

Aliases: CD71 antigen; T9; TFRC; TR; TfR1; Transferrin receptor protein 1; Trfr; p90

Recommended Dilutions:  

WB 1:1000-1:2000

 

IHC-P 1:100-1:200

 

IP 1:20-1:50

 

FC 1:50-1:100

Storage: Rabbit IgG in 10mM phosphate buffered saline, pH7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. Store at +4 short term. Store at -20 long term. Avoid repeated freeze-thaw cycle.

Background: Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity).

Western blot analysis of Transferrin Receptor (CD71) expression in HeLa cell lysate.

For Research Use Only. Not for Use in Diagnostic Procedures. 

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