Basic Information:

Storage: Rabbit IgG in 10mM phosphate buffered saline, pH7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. Store at +4℃ short term. Store at -20℃ long term. Avoid repeated freeze-thaw cycle.

Background: The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. 

Western blot analysis of PGC1 alpha/beta expression in (1) HeLa cell lysate; (2) NIH 3T3 cell lysate; (3) C6 cell lysate.

For Research Use Only. Not for Use in Diagnostic Procedures.