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Anti-Niemann Pick C1 Monoclonal Antibody

应用范围: WB, IHC-P, IHC-F, ICC/IF, FC
产品类型: 兔单抗
保存温度: -20℃
产地: YOBIBIO
UniProt ID: O15118
宿主: Rabbit
克隆性: Monoclonal
修饰: Unmodified
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Basic Information:

UniProt ID: O15118

Calculated Mol Weight: 142 kDa

Host: Rabbit

Observed Mol Weight: 180 kDa

Clonality: Monoclonal

Reactivity: Human, Mouse, Rat

Source: Recombinant Rabbit mAb

Applications: WB, IHC-P, IHC-F, ICC/IF, FC

Isotype: Rabbit IgG

Purification: Affinity-chromatography

Modification: Unmodified

Immunogen: A synthesized peptide

Aliases: Niemann Pick C1 protein precursor; NPC; NPC1

Recommended Dilutions:  

WB 1:1000-1:2000

 

IHC-P 1:100-1:200

 

IHC-F 1:50-1:200

 

ICC/IF 1:50-1:200

 

FC 1:20-1:100

Storage: Rabbit IgG in 10mM phosphate buffered saline, pH7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. Store at +4 short term. Store at -20 long term. Avoid repeated freeze-thaw cycle.

Background: Intracellular cholesterol transporter which acts in concert with NPC2 and plays an important role in the egress of cholesterol from the endosomal/lysosomal compartment.Unesterified cholesterol that has been released from LDLs in the lumen of the late endosomes/lysosomes is transferred by NPC2 to the cholesterol-binding pocket in the N-terminal domain of NPC1.


Western blot analysis of Niemann Pick C1 expression in HepG2 cell lysate.

For Research Use Only. Not for Use in Diagnostic Procedures. 

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保存温度:-20℃
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